Certain conditions can be passed down through dominant inheritance. Dominant inheritance means that a mutation in a gene can cause symptoms in a person even if the second copy of that gene is normal.
Our genes can be passed down, or inherited, from our mom and dad in several different ways. One way is called dominant inheritance.
Dominant inheritance means that a mutation in a gene can cause symptoms in a person, even if the second copy of that same gene is normal. Dominant inheritance causes “dominant conditions.”
One copy of each gene comes from mom and the other from dad.
A person can either inherit a dominant condition from a parent, or they can be the first person to have the condition in their family if the mutation arose as a new, or “de novo,” change in them.
You might be able to recognize dominant inheritance in your family because you see a condition being passed from one generation to the next. For example, you know that your mom, you, and your child all have hearing loss.
If we think about a dominant condition being passed from one generation to the next, you might be wondering why some people are affected and some people are not. This is because a parent with a dominant condition can pass on either their gene with the mutation, or their normal gene.
If a child gets the mutation from their parent they will, in general, be affected with similar features. However, they won’t always be exactly the same — individual features and severity may vary.
A child who inherits the normal copy of the gene will not be affected.
Anyone affected with a dominant condition has a 50% chance in each pregnancy to pass it on. It is very important to recognize that a parent does not control which gene copy gets passed on to their child.
In a de novo dominant condition, the parents have very little risk of having another child affected. However, the person with the condition will now have a 50% chance of passing it on to their children.